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Statistical effects of the repair mechanisms of cells damaged by ionizing radiation / Statystyczne efekty reperacji komórek uszkodzonych w wyniku naświetlania promieniowaniem jonizującym (24–31)

Autorzy: Agata Kowalska, Konrad Czerski, Mateusz Kaczmarski, Wiktoria Pereira, Polina Kutsalo, Ekaterina Zaytseva


A new method to estimate the effectiveness of repair mechanisms is presented. The method is based on the reduction of variance of observed chromosomal aberrations in relation to the values expected for the Poisson statistics. This effect is known in other fields of physics as the Fano factor and can be applied to various tissues and for both low and high LET (Linear Energy Transfer) radiation’s types. By exploiting the new method, distributions of chromosomal aberrations in peripheral blood lymphocytes observed for gamma and 150 MeV proton radiation, have been compared.


Słowa kluczowe: chromosomal aberrations, repair mechanisms, Poisson statistics, Fano factor

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